%0 Journal Article
%T Infection status and risk factors of HIV, HBV, HCV, and syphilis among drug users in Guangdong, China - a cross-sectional study
%A Jie Wu
%A Jinying Huang
%A Duorong Xu
%A Ciyong Lu
%A Xueqing Deng
%A Xiaolan Zhou
%J BMC Public Health
%D 2010
%I BioMed Central
%R 10.1186/1471-2458-10-657
%X A cross-sectional study on drug use behaviors, sex behaviors, and presence of antibodies to HIV, HCV, Treponema pallidum, and surface antigen of HBV (HBsAg) was conducted among drug users recruited from 3 detoxification centers in Qingyuan, Guangdong, China. Risk factors for each of four infections were analyzed with logistic regression model.A total of 740 subjects were recruited, the median age was 31 years old (range 24-38). The seroprevalence rates of HIV, HBsAg, HCV and syphilis were 4.6%, 19.3%, 71.6% and 12.6%, respectively. Risk factors for HIV were intravenous drug use and co-infection with syphilis. Having a regular sexual partner who was a drug user was considered to be a risk factor for HBV. Intravenous drug use was a risk factor for HCV. However, the consistent use of condoms with commercial sex partners was protective for HCV infection. Compared to drug users living in urban area, those living in rural areas were more likely to be infected with syphilis, and there was an association between commercial sex and syphilis.The prevalence of HIV, HBV, HCV and syphilis were high among drug users in detoxification centers in Qingyuan, thus, risk reduction programs for the drug user population is urgently required.Since adopting a free market economy and an open door policy in 1978, China has witnessed a remarkable increase in sexually transmitted infections (STIs) and HIV [1]. By the end of 2007, the cumulative number of HIV positive individuals reported in China was 223,501, including 62,838 AIDS cases and 22,205 recorded deaths, 38.5% of reported HIV positive people were infected via intravenous drug use (IDU) [2]. Meanwhile, the prevalence of some blood-borne and sexually transmitted infections, including HBV, HCV and syphilis among drug users is also alarming. Several Studies in China have confirmed that the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis in drug user population is higher than that in the general population. For
%U http://www.biomedcentral.com/1471-2458/10/657