%0 Journal Article
%T Augmented annotation and orthologue analysis for Oryctolagus cuniculus: Better Bunny
%A Douglas B Craig
%A Sujatha Kannan
%A Alan A Dombkowski
%J BMC Bioinformatics
%D 2012
%I BioMed Central
%R 10.1186/1471-2105-13-84
%X Using data extracted from several public bioinformatics repositories we created Better Bunny, a database and query tool that extensively augments the available functional annotation for rabbit genes. Using the complete set of target genes from a commercial rabbit gene expression microarray as our benchmark, we are able to obtain functional information for 88 % of the genes on the microarray. Previously, functional information was available for fewer than 10 % of the rabbit genes.We have developed a freely available, web-accessible bioinformatics tool that enables investigators to quickly and easily perform extensive functional analysis of rabbit genes (http://cptweb.cpt.wayne.edu webcite). The software application fills a critical void for a wide range of biomedical research that relies on the rabbit model and requires characterization of biological function for large sets of genes.
%K Rabbit
%K Genome
%K Annotation
%K Orthologue
%K Microarray
%K Functional analysis
%U http://www.biomedcentral.com/1471-2105/13/84/abstract