%0 Journal Article %T Risk assessment of PM2.5 to child residents in Brazilian Amazon region with biofuel production %A Beatriz F¨¢tima de Oliveira %A Eliane Ignotti %A Paulo Artaxo %A Paulo do Nascimento Saldiva %A Washington Junger %A Sandra Hacon %J Environmental Health %D 2012 %I BioMed Central %R 10.1186/1476-069x-11-64 %X Risk assessment methodology was applied to estimate the risk quotient in two scenarios of exposure according to local seasonality. The potential dose of PM2.5 was estimated using the Monte Carlo simulation, stratifying the population by age, gender, asthma and Body Mass Index (BMI).Male asthmatic children under the age of 8 at normal body rate had the highest risk quotient among the subgroups. The general potential average dose of PM2.5 was 1.95£¿¦Ìg/kg.day (95% CI: 1.62 ¨C 2.27) during the dry scenario and 0.32£¿¦Ìg/kg.day (95% CI: 0.29 ¨C 0.34) in the rainy scenario. During the dry season, children and adolescents showed a toxicological risk to PM2.5 of 2.07£¿¦Ìg/kg.day (95% CI: 1.85 ¨C 2 .30).Children and adolescents living in the Subequatorial Brazilian Amazon region were exposed to high levels of PM2.5 resulting in toxicological risk for this multi-pollutant. The toxicological risk quotients of children in this region were comparable or higher to children living in metropolitan regions with PM2.5 air pollution above the recommended limits to human health.Air pollution is one of the several environmental factors that is having a serious impact on human health and quality of life. Particulate matter (PM) air pollution, measuring less than 2.5£¿¦Ìm, has been the focus of international concern due to its diverse contribution to the global burden of disease. There have been more than 2,000 peer-reviewed studies published since 1997 linking it to strokes, various respiratory and cardiovascular problems and premature death. Unfortunately, the majority of the planet still resides in areas where the World Health Organization Air Quality Guidelines of 10£¿¦Ìg/m3 (annual) and 25£¿¦Ìg/m3 (24-hour period) is exceeded [1].Global estimates of ambient pollution levels have relied heavily upon either econometric or transport models mostly due to the lack of ground-level measurements of air pollution, especially PM2.5, which have been unavailable for most of the planet [1]. Yet, the distinctiv %K Particulate matter %K Biomass burning %K Risk assessment %K Health effects %K Children %K Adolescents and Brazilian Amazon %U http://www.ehjournal.net/content/11/1/64