%0 Journal Article
%T Liposarcoma of the tongue: case report and review of the literature
%A Marika R Dubin
%A Edward W Chang
%J Head & Face Medicine
%D 2006
%I BioMed Central
%R 10.1186/1746-160x-2-21
%X We present a case of well-differentiated liposarcoma of the tongue occuring in a 39 year old man, treated with surgical excision. At 14 years of follow-up, the patient remains free of disease.Liposarcoma of the head and neck is rare, and may easily be misdiagnosed clinically. The diagnosis is made histologically. Clinical behavior is related to histopathologic subtype. Wide surgical excision is the treatment of choice, with limited data to support the use of radiation or chemotherapy. Our case represents the longest follow-up period for a tongue liposarcoma, with 14 years disease-free following surgical extirpation.Liposarcoma is a malignant mesenchymal neoplasm that arises from adipose tissue, most commonly in the retroperitoneum and lower extremities. Liposarcoma of the head and neck is rare, representing 5.6% to 9% of cases in large series [1-3]. Common sites of occurrence in the head and neck region include the larynx, hypopharynx, oral cavity, orbit, scalp and soft tissues of the neck. In a recent review, Nikitakis et al [4] identified 44 cases of oral liposarcoma published in the English language literature between 1944 and 2001. Liposarcoma of the oral cavity demonstrates a predilection for the cheek [4-6], with other sites including the floor of the mouth, palate, gingiva, mandible, and tongue. To our knowledge, there have been only 12 previously reported cases of liposarcoma of the tongue in the English language literature (Table 1). We present a case of well-differentiated liposarcoma of the tongue and review the current literature.A 39 year old man presented in late 1990 to an outside institution with a right lateral tongue mass. His past medical history was significant only for alcohol abuse and a history of syphilis. His physical examination revealed a 1 กม 1 cm mass on the right lateral aspect of the tongue (Figure 1). The mass was felt to be a traumatic lesion secondary to abrasion against a fractured tooth. The fractured tooth was extracted. Six month
%U http://www.head-face-med.com/content/2/1/21