%0 Journal Article %T A wavelet-based ECG delineation algorithm for 32-bit integer online processing %A Luigi Y Di Marco %A Lorenzo Chiari %J BioMedical Engineering OnLine %D 2011 %I BioMed Central %R 10.1186/1475-925x-10-23 %X This paper presents a 32-bit integer, linear algebra advanced approach to online QRS detection and P-QRS-T waves delineation of a single lead ECG signal, based on WT.The QRS detector performance was validated on the MIT-BIH Arrhythmia Database (sensitivity Se = 99.77%, positive predictive value P+ = 99.86%, on 109010 annotated beats) and on the European ST-T Database (Se = 99.81%, P+ = 99.56%, on 788050 annotated beats). The ECG delineator was validated on the QT Database, showing a mean error between manual and automatic annotation below 1.5 samples for all fiducial points: P-onset, P-peak, P-offset, QRS-onset, QRS-offset, T-peak, T-offset, and a mean standard deviation comparable to other established methods.The proposed algorithm exhibits reliable QRS detection as well as accurate ECG delineation, in spite of a simple structure built on integer linear algebra.The electrocardiogram (ECG) is the recording of the electrical activity of the heart by means of electrodes placed on the body surface. It is the most commonly used non-invasive test in primary care for heart rate and rhythm-related abnormalities detection [1,2]. In recent years the interest for the ECG signal analysis has extended from clinical practice and research to disciplines such as cognitive psychophysiology [3,4], physical training [5,6] and rehabilitation [7].Many non-diagnostic applications do not require the full 12-lead setup of clinical ECG, employing a limited number of electrodes. In some cases a single lead setup, requiring only three electrodes, is sufficient. Such applications focus on ambulatory ECG monitoring, namely in unconstrained conditions, in which subjects perform normal activities as in their daily life [4], [8-10].Ambulatory ECG analysis requires processing of signals which are affected by considerable noise, mainly caused by electrode motion and muscular activity, more prominently than in resting ECG recordings, and by power-line coupling. Moreover, emerging wearable technologi %U http://www.biomedical-engineering-online.com/content/10/1/23