%0 Journal Article
%T Cylindroma of the breast: a case report and review of the literature
%A Amr Mahmoud
%A David H Hill
%A Martin J O'Sullivan
%A Michael W Bennett
%J Diagnostic Pathology
%D 2009
%I BioMed Central
%R 10.1186/1746-1596-4-30
%X Cylindroma of the breast is a rare benign entity. To date only nine cases have been published to our knowledge. Although the appearance of cylindroma of the breast is identical to that of its dermal counterpart these lesions arise within the breast parenchyma. It is usually present as a solitary lesion, or may be associated with other lesions. We present a case detected by a national mammographic screening program. We review the radiology, histology, clinical course and discuss the previous cases in the literature. We discuss its differentiation from the main differential diagnosis, solid variant of adenoid cystic carcinoma.A 62 year old woman was invited to present for breast screening by the National Breast Cancer Screening Service (BreastCheck). She had neither significant medical nor family history. A 1.6 cm circumscribed reasonably defined mass was detected on screening mammography in the 3 o'clock position of her right breast (Figure 1). Ultrasound imaging showed a corresponding heterogeneous mass containing areas of notably increased echogenicity (Figure 2). On physical examination the lesion was not palpable. There were no skin or nipple changes, and no axillary or supraclavicular adenopathy. The lesion was considered suspicious but probably benign, and thus accorded a radiological grading (NHS breast screening system) score of M3 and U3 on mammographic and ultrasonic imaging respectively. An ultrasound guided core needle biopsy was performed. The patient underwent a right breast excision. The excision specimen weighted 13 gm, and measured 3.8 กม 3.2 กม 1.7 cm. Specimen radiography revealed a central density.On serially sectioning the specimen a firm tumour measuring 1.6 cm in maximum dimension was identified. Representative sections were submitted. An unencapsulated relatively circumscribed tumor was identified on microscopy. The tumor was composed of tightly arranged nests of cells with a characteristic "jig-saw" or "mosaic" appearance at low power (Figure 3
%U http://www.diagnosticpathology.org/content/4/1/30