%0 Journal Article
%T Metabolic syndrome in type 2 diabetes: comparative prevalence according to two sets of diagnostic criteria in sub-Saharan Africans
%A Andre P Kengne
%A Serge N Limen
%A Eugene Sobngwi
%A Cath¨¦rine FT Djouogo
%A Christophe Nouedoui
%J Diabetology & Metabolic Syndrome
%D 2012
%I BioMed Central
%R 10.1186/1758-5996-4-22
%X We collected clinical and biochemical data for 308 patients with type 2 diabetes (men 157) at the National Obesity Center of the Yaounde Central Hospital, Cameroon. Concordance was assessed with the use of the Kappa statistic.Mean age (standard deviation) was 55.8 (10.5) years and the median duration of diagnosed diabetes (25th¨C75th percentiles) was 3£¿years (0.5¨C5.0), similarly among men and women. The prevalence of MS was 71.7% according to the IDF criteria and 60.4% according to NCEP-ATP III criteria. The prevalence was significantly higher in women than in men independently of the criteria used (both p£¿<£¿0.001). Overall concordance between both definitions was low to average 0.51 (95% confidence interval: 0.41¨C0.61). Combining the two sets of criteria marginally improved the yield beyond that provided by the IDF criteria alone in men, but not in the overall population and in women.The IDF and NCEP-ATP III criteria do not always diagnose the same group of diabetic individuals with MS and combining them merely increases the yield beyond that provided by the IDF definition alone. This study highlights the importance of having a single unifying definition for MS in our setting.Metabolic syndrome (MS) is a group of clinical and biological abnormalities that confers a greater risk of type 2 diabetes, cardiovascular (CVD) [1] and liver diseases [2]. The different components of MS were initially described by Reaven in 1988 under the appellation of ¡°syndrome X¡± [3]. These include abdominal obesity, higher-than-optimal blood pressure, disorders of glucose metabolism and abnormal lipid profile [4]. Although still debated, the underlying feature of all these abnormalities seems to be insulin resistance [5]. Regardless of the presence of any abnormalities of glucose metabolism, individuals with MS are at increased risk of type 2 diabetes [6]. The co-occurrence of diabetes mellitus and MS potentiates the cardiovascular risk associated with each of the two conditions. Character
%K Metabolic syndrome
%K Diabetes mellitus
%K Prevalence
%K Concordance
%K Cameroon
%K Sub-Saharan Africa
%U http://www.dmsjournal.com/content/4/1/22