%0 Journal Article
%T Depressed mood, glycaemic control and functional capacity in overweight/obese men with and without type 2 diabetes
%A Itamar Levinger
%A Steve Selig
%A George Jerums
%A Andrew Stewart
%A Cadeyrn J Gaskin
%A David L Hare
%J Diabetology & Metabolic Syndrome
%D 2012
%I BioMed Central
%R 10.1186/1758-5996-4-46
%X Fifty seven overweight/obese men with (n£¿=£¿19, age£¿=£¿54.2£¿¡À£¿7.4 yrs, BMI£¿=£¿32.3£¿¡À£¿6.7 kg£¿m-2) and without T2DM (n£¿=£¿38, age£¿=£¿51.1£¿¡À£¿6.8 yrs, BMI£¿=£¿29.9£¿¡À£¿4.5kg£¿m-2, p£¿>£¿0.05 between groups) participated. The men completed measures of depressed mood and health-related quality of life (HRQL) and underwent the following assessments: fasting blood lipids and glucose, HbA1c, anthropometric measurements, VO2peak, muscle strength, and physical function.Compared to men without T2DM, men with T2DM had higher depressed mood (p£¿=£¿0.05, ¦Ç2£¿=£¿0.07), as well as lower perceived general health (p£¿<£¿.01, ¦Ç2£¿=£¿0.24) and social functioning (p£¿=£¿.01, ¦Ç2£¿=£¿0.10). Men with T2DM also had lower VO2peak (21.8£¿¡À£¿5.3 versus 25.8£¿¡À£¿5.4 ml£¿kg-1£¿min-1, p£¿<£¿.01, ¦Ç2£¿=£¿0.11) and muscle strength (3.3£¿¡À£¿0.8 versus 3.7£¿¡À£¿0.7 kg£¿kg-1, p£¿=£¿0.08, ¦Ç2£¿=£¿0.06), as well as being slower to complete physical performance tasks (27.2£¿¡À£¿5.2 versus 24.2£¿¡À£¿2.8 sec, p£¿<£¿0.01, ¦Ç2£¿=£¿0.13). In those with T2DM, depressed mood was highly correlated with most HRQL subscales. For the combined cohort, depressed mood was correlated with fasting glucose (r£¿=£¿0.31, p£¿=£¿0.012) but not the functional measures.Men with T2DM have higher levels of depressed mood compared to men without T2DM. Glycaemic control, but not functional capacities, is associated with depressed mood in the study cohort.Most people with type 2 diabetes (T2DM) are overweight or obese [1] and, compared to people without diabetes, have double the risk for depression [2]. Aside from experiencing poor health, people with T2DM have higher incidence of functional limitations, particularly if they have poor glycaemic control [3].The relationship between diabetes and depression is bidirectional [4,5]. Up to a point, the severity of either condition seems to be associated with the chronicity of the other. For example, in community-dwelling older adults, depressive symptoms and HbA1c levels rise in tandem until HbA1c levels reach about 8%, beyond which the severity of
%K Aerobic power
%K Cardiac Depression Scale
%K Depression
%K Glycaemic control
%K Type 2 diabetes
%U http://www.dmsjournal.com/content/4/1/46