%0 Journal Article
%T B-Type natriuretic peptide assessment in coronary arterial bypass graft surgery
%A W Homena
%A P Rezende
%A A Camarozano
%A J Fonseca
%A A Pyramides
%A D Oliveira
%A J Magalhaes
%A V Carreira
%J Critical Care
%D 2003
%I BioMed Central
%R 10.1186/cc2211
%X We sought to correlate the clinical and hemodynamic features in postoperative (PO) stay and the levels of BNP.A prospective and observational study. We assessed the level of BNP (imunofluorescence ¨C Triage£¿) at 1 and 24 hours PO. A BNP level above a cutoff point of 100 pg/ml was found to be highly sensitive and specific for the diagnosis of cardiac heart failure. The population consisted of two groups: group A had levels below 100 pg/ml and group B was above this level. Evaluated at 1 hour of PO stay were: time of cardiopulmonary bypass (CBP), hidric balance (HB), mean arterial pressure (MAP), heart rate (HR), central venous pressure (CVP), pO2 and FiO2 ratio (P/F), mechanical ventilation time (MV) and O2 central venous saturation (VO2SAT). The left ventricular function was assessed by two-dimensional echocardiography in the preoperative period (Simpson method) and values under 40% were considered ventricular dysfunction. The Student t-test was used for comparison between the found means.We investigated 17 patients (three women, median age 58.4 years old; standard deviation = 9.7). Group A was composed of 11 patients and group B of six patients. No statistical difference was found regarding CPB, HB, MAP, HR, CVP, P/F and VO2SAT, whereas the MV time in group A was 211.3 ¡À 229 min, with regard to group B being 520.8 ¡À 332.9 min (P = 0.038). At 24 hours PO, the BNP mean level (327.8 ¡À 206.9 pg/ml) was found in 13 patients (76.4%).Left ventricular dysfunction was observed in two patients of group B.Although there was a reduced number of patients, these findings suggest that the BNP levels were related to the mechanical ventilatory time.
%U http://ccforum.com/content/7/S3/P15