%0 Journal Article
%T Retrospective Analysis of Metabolic Syndrome: Prevalence and Distribution in Executive Population in Urban Pakistan
%A Niloufer Sultan Ali
%A Ali Khan Khuwaja
%A Adnan-ur-Rahman
%A Kashmira Nanji
%J International Journal of Family Medicine
%D 2012
%I Hindawi Publishing Corporation
%R 10.1155/2012/649383
%X Background. Metabolic Syndrome (MetS) is a major public health concern. Objective. The aim of this study was to estimate the frequency of MetS, its components, and factors associated with MetS amongst apparently healthy individuals in Pakistan. Methods. A retrospective cross-sectional study was conducted at the executive Clinics of Aga Khan Hospital, Pakistan. Medical records of patients aged ¡Ý18 years visiting the clinics from July 2011 to December 2011 were consecutively reviewed. Records in which either MetS components data or 10% of overall data was missing were excluded. A total of 1329 participants¡¯ records was included in final analysis. Data was analyzed using SPSS version 19 and multivariable logistic regression was used to identify the factors associated with MetS. Results. A total of 847 (63.7%) participants had MetS; mean age of the participants were 47.6 ¡À 11.6 years. About 70.4% were males and 29.6% were females. Approximately 70% of participants had BMI ¡Ý25£¿kg/m2. MetS was associated with male gender (AOR£¿=£¿2.1; 95%£¿C.I: 1.6¨C3.2) and history of diabetes among parents (AOR£¿=£¿3.0; 95%£¿C.I: 1.6¨C6.0). Conclusion. This study shows that a large proportion of population has MetS and is overweight or obese. This requires urgent interventions on part of health care providers¡¯ especially family physicians. Educating masses about life style factors can make a difference. Further researches on this issue are warranted. 1. Introduction Globally, Metabolic Syndrome (MetS) has become a public health concern and is a major cause of morbidity and mortality. Many studies have provided strong evidence for the association of MetS with acute coronary syndrome [1¨C4]. In health care services the value of MetS derives largely from its potential to reduce the risk of cardiovascular disease in the general population by treating the disease [5]. There has been much a debate on the definition of MetS. However, recent definition of MetS given by American heart association and the National heart, Lung and Blood Institute (AHA/NHLBI) in 2005 declared that a clinical diagnosis of MetS can be established if any three of the following factors are present, elevated triglyceride level (TG): elevated waist circumference, decreased HDL-cholesterol (HDL) level, elevated fasting glucose, and elevated blood pressure [6]. The estimated prevalence of MetS in general population is between 17 and 25% [7]. Various studies have demonstrated that the major causes leading to MetS are insulin resistance, obesity, and genetic predisposition [8]. Several cross-sectional studies have
%U http://www.hindawi.com/journals/ijfm/2012/649383/