%0 Journal Article
%T Genome-wide mapping of NBS-LRR genes and their association with disease resistance in soybean
%A Yang Kang
%A Kil Kim
%A Sangrea Shim
%A Min Yoon
%A Suli Sun
%A Moon Kim
%A Kyujung Van
%A Suk-Ha Lee
%J BMC Plant Biology
%D 2012
%I BioMed Central
%R 10.1186/1471-2229-12-139
%X A total of 319 genes were determined to be putative NBS-LRR genes in the soybean genome. The number of NBS-LRR genes on each chromosome was highly correlated with the number of disease resistance QTL in the 2-Mb flanking regions of NBS-LRR genes. In addition, the recently duplicated regions contained duplicated NBS-LRR genes and duplicated disease resistance QTL, and possessed either an uneven or even number of NBS-LRR genes on each side. The significant difference in NBS-LRR gene expression between a resistant near-isogenic line (NIL) and a susceptible NIL after inoculation of Xanthomonas axonopodis pv. glycines supports the conjecture that NBS-LRR genes have disease resistance functions in the soybean genome.The number of NBS-LRR genes and disease resistance QTL in the 2-Mb flanking regions of each chromosome was significantly correlated, and several recently duplicated regions that contain NBS-LRR genes harbored disease resistance QTL for both sides. In addition, NBS-LRR gene expression was significantly different between the BLP-resistant NIL and the BLP-susceptible NIL in response to bacterial infection. From these observations, NBS-LRR genes are suggested to contribute to disease resistance in soybean. Moreover, we propose models for how NBS-LRR genes were duplicated, and apply Ks values for each NBS-LRR gene cluster.R genes are a key component of gene interactions between plants and biotrophic bacteria and often function to regulate resistance to bacterial invasion [1]. Recent studies have proposed the ¡®zigzag model¡¯ to describe the resistance of plants in the context of the co-evolution between invader and host [2]. The first phase of plant defense is pathogen molecular pattern-triggered immunity (PTI) by which the immune system of the plant recognizes a broad range of pathogens with conserved molecular patterns, thereby conferring non-host resistance. In the second phase, effector-triggered immunity (ETI) detects effectors injected into the plant cell with
%K Genome duplication
%K NBS-LRR
%K Soybean
%K Transcriptome analysis
%U http://www.biomedcentral.com/1471-2229/12/139