%0 Journal Article %T Cost of clinical events in health economic evaluations in Germany: a systematic review %A Monika Scheuringer %A Narine Sahakyan %A Karl J Krobot %A Volker Ulrich %J Cost Effectiveness and Resource Allocation %D 2012 %I BioMed Central %R 10.1186/1478-7547-10-7 %X In Germany, the Institute for Quality and Efficiency in Health Care (IQWiG) has been legally empowered to assess the increase in benefit as well as the relationship of benefits and costs for drugs and healthcare procedures. IQWiG has recently published a working paper on cost estimation in cost¨Cbenefit assessments in Germany [1]. In this document, it is acknowledged that there is potential for standardization of costing methodology to improve the comparability of health economic evaluations. Lists of agreed unit costs (so-called standard cost lists) that supplement guidelines for health economic break at evaluation in other countries (e.g. Australia [2], Canada [3,4], and the Netherlands [5]) are cited as examples of such standardization. In addition, the ¡®Methods in Health Economic Evaluation¡¯ Working Group (AG Methoden der gesundheits£¿konomischen Evaluation [AG MEG]) of the German Society for Social Medicine and Prevention have developed an approach to standardizing cost estimates [6]. In general, however, such lists do not comprise agreed costs for frequently observed clinical events as estimates for the actual costs accrued (so-called costs for clinical events).Costs for clinical events are essential for creating health economic models that are able to accurately simulate both the health outcomes and cost of different treatment options by incorporating evidence from a variety of sources. Ideally, the way in which these costs are obtained and the cost components included, should be described in the reporting of each study. We conducted a systematic literature review of costs for clinical events used in health economic evaluations in Germany from 2005 to 2009 in order to provide insight into the derivation of these costs and to assess the potential for providing future standard lists for clinical events.A systematic literature review was conducted to determine the costs for clinical events that are relevant to patients with diabetes mellitus, according to Preferre %K Costs %K Diabetes mellitus %K Germany %K Health economics %U http://www.resource-allocation.com/content/10/1/7