%0 Journal Article
%T What motivates British parents to consent for research? A questionnaire study
%A Helen M Sammons
%A Maria Atkinson
%A Imti Choonara
%A Terence Stephenson
%J BMC Pediatrics
%D 2007
%I BioMed Central
%R 10.1186/1471-2431-7-12
%X The setting was a multi-centre randomised but non-blinded equivalence trial of oral versus intravenous (IV) treatment for community acquired pneumonia in previously well children aged 6 months to 16 years in the UK (PIVOT Study). Parents were sent a postal questionnaire at the end of the study which included open and closed-ended questions. Fishers Exact Test was used to analyse associations in non parametric categorical data.243 children were recruited into the PIVOT study. Of a possible 235, 136 questionnaires were returned (response rate 59%). Of those questionnaires returned; 98% of parents remembered consenting, 95% felt they were given enough time to make their decision and 96% felt they received enough information. Major reasons for participation were benefit to other children in the future 31%, contribution to science 27%, benefit to their own child 18%. Most parents (85%) did not feel obliged to participate. 62% felt there was an advantage to taking part and 18% felt there was a disadvantage. 91% of parents said they would take part in a similar study in the future, stating influences on their decision being benefit to their own child (91%) and benefit to all children (89%).The major motivation in parents consenting for their previously well child to participate in an RCT of therapy for an acute medical illness was to increase medical knowledge in the future. Most saw an advantage in taking part in the trial and did not feel obliged to participate.Research in a child is different to that in adults. Informed consent is essential for recruitment into a randomised controlled trial. The informed consent process is undertaken in the majority of paediatric trials by the child's parent. It has been found that a child's ability to assent or consent to research under the age of 9 years is limited [1]. Recruitment is said to be difficult within paediatric trials and quoted as being the single most difficult problem to overcome; leading to delays, increased costs and
%U http://www.biomedcentral.com/1471-2431/7/12