%0 Journal Article
%T Resting heart rate as a predictor of metabolic dysfunctions in obese children and adolescents
%A Ismael F Freitas J¨²nior
%A Paula A Monteiro
%A Loreana S Silveira
%A Suziane U Cayres
%A B¨˘rbara M Antunes
%A Karolynne N Bastos
%A Jamile S Codogno
%A Jo£żo Paulo J Sabino
%A R£żmulo A Fernandes
%J BMC Pediatrics
%D 2012
%I BioMed Central
%R 10.1186/1471-2431-12-5
%X The sample was composed of 180 obese children and adolescents, aged between 7-16 years. Whole-body and segmental body composition were estimated by Dual-energy X-ray absorptiometry. Resting heart rate (RHR) was measured by heart rate monitors. The fasting blood samples were analyzed for serum triglycerides, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and glucose, using the colorimetric method.Fasting glucose, TC, triglycerides, HDL-C, LDL-C and RHR were similar in both genders. The group of obese subjects with a higher RHR presented, at a lower age, higher triglycerides and TC. There was a significant relationship between RHR, triglycerides and TC. In the multivariate model, triglycerides and TC maintained a significant relationship with RHR independent of age, gender, general and trunk adiposity. The ROC curve indicated that RHR has a high potential for screening elevated total cholesterol and triglycerides as well as dyslipidemia.Elevated RHR has the potential to identify subjects at an increased risk of atherosclerosis development.Over the last few decades obesity has reached epidemic proportions and become one of the major public health targets worldwide. Several researches indicate that obesity tracks from childhood to adulthood and constitutes a risk factor in the development of chronic diseases [1]. A high amount of body fatness is responsible for releasing a great amount of inflammatory adipokines into the bloodstream which has an important role in the pathogenesis of many chronic diseases [2,3], and also in the changes of sympathetic and parasympathetic activity in children and adolescents, which can result in an increased resting heart rate (RHR) [4-7].In adults, the use of RHR as screening index for cardiovascular risk has been postulated [8,9] and supported by studies that reported its relationship to mortality, independent of abdominal obesity [10,11], but few studies are found which
%K Obesity
%K child
%K adolescent
%K metabolic dysfunctions
%K resting heart rate
%U http://www.biomedcentral.com/1471-2431/12/5