%0 Journal Article %T Immediate effects of acupuncture on biceps brachii muscle function in healthy and post-stroke subjects %A Ana Fragoso %A Arthur S Ferreira %J Chinese Medicine %D 2012 %I BioMed Central %R 10.1186/1749-8546-7-7 %X A randomized clinical trial, with parallel groups, single-blinded study design, was conducted with 32 healthy subjects and 15 post-stroke patients with chronic hemiparesis. Surface electromyography from biceps brachii during maximal isometric voluntary tests was performed before and after 20-min intermittent, and manual stimulation of acupoints Quchi (LI11) or Tianquan (PC2). Pattern differentiation was performed by an automated method based on logistic regression equations.Healthy subjects showed a decrease in the root mean-squared (RMS) values after the stimulation of LI11 (pre: 1.392 ¡À 0.826 V; post: 0.612 ¡À 0.0.320 V; P = 0.002) and PC2 (pre: 1.494 ¡À 0.826 V; post: 0.623 ¡À 0.320 V; P = 0.001). Elbow flexion maximal isometric voluntary contraction (MIVC) was not significantly different after acupuncture stimulation of LI11 (pre: 22.2 ¡À 10.7 kg; post: 21.7 ¡À 9.5 kg; P = 0.288) or PC2 (pre: 18.8 ¡À 4.6 kg; post: 18.7 ¡À 6.0 kg; P = 0.468). Post-stroke patients did not exhibit any significant decrease in the RMS values after the stimulation of LI11 (pre: 0.627 ¡À 0.335 V; post: 0.530 ¡À 0.272 V; P = 0.187) and PC2 (pre: 0.601 ¡À 0.258 V; post: 0.591 ¡À 0.326 V; P = 0.398). Also, no significant decrease in the MIVC value was observed after the stimulation of LI11 (pre: 9.6 ¡À 3.9 kg; post: 9.6 ¡À 4.7 kg; P = 0.499) or PC2 (pre: 10.7 ¡À 5.6 kg; post: 10.2 ¡À 5.3 kg; P = 0.251). Different frequency of patterns was observed among healthy subjects and post-stroke patients groups (¦Ö2 = 9.759; P = 0.021).Manual acupuncture provides sufficient neuromuscular stimuli to promote immediate changes in motor unit gross recruitment without repercussion in maximal force output in healthy subjects. Post-stroke patients did not exhibit significant reduction on the myoelectric activity and maximal force output after manual acupuncture and needs further evaluation with a larger sample.Brazilian Clinical Trials Registry RBR-5g7xqh.Deaths related to cardiovascular disease are expected to be 24 mil %U http://www.cmjournal.org/content/7/1/7