%0 Journal Article
%T Simultaneous Determination of Sulbactam Sodium and Cefoperazone Sodium in Sulperazon by High Performance Liquid Chromatography<br>高效液相色谱法测定舒普深中的舒巴坦钠和头孢哌酮钠
%A LI Fa-sheng
%A XU Zhi-xiu
%A XIAO Hong-bin
%A LIANG Xin-mian
%A <br>李发胜
%A 徐智秀
%A 肖红斌
%A 梁鑫淼
%J 色谱
%D 2000
%I 
%X A reversed-phase, isocratic high performance liquid chromatographic method with acid mobile phase can separate sulbactam and cafoperazone within 12 minutes. Column packed with Hypersil ODS2(250 mm x 4.6 mm i.d., 5 microns) was manufactured by Dalian Elite Company. Mobile phase is composed of water (adjusted to pH 4.0 with 1% phosphoric acid) and acetonitrile (80:20, V/V). The detection was performed at 210 nm and the injection volume was 2 microL. Cefoperazone and sulbactam have good linearity in the ranges of 100 mg/L to 800 mg/L and 100 mg/L to 1,000 mg/L with the correlation coefficients of 0.9991 and 0.9997 respectively. This method is easily to be operated and can be applied for manufacturing and medicinal study.
%K high performance liquid chromatography
%K Sulperazon
%K sulbactam sodium
%K cefoperazone sodium(<br>舒普深
%K 舒巴坦钠
%K 头孢哌酮钠
%K 测定
%K HPLC
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=9BA2AC08419A7FD87D06B74F1CC4EDD3&yid=9806D0D4EAA9BED3&vid=13553B2D12F347E8&iid=B31275AF3241DB2D&sid=20C3B205768D55E0&eid=E3D3D8D1B650AE1E&journal_id=1000-8713&journal_name=色谱&referenced_num=1&reference_num=6