%0 Journal Article
%T Purification of L-Lysine in Simulated Moving Bed and Fixed-Bed Chromatography
%A OBATJAZI Seyed Mortaza
%A SHOJAOSADATI Seyed Abbas
%A KARBASY Seyed Mojtaba
%A
ROBATJAZI Seyed Mortaza
%A SHOJAOSADATI Seyed Abbas
%A KARBASY Seyed Mojtaba
%J É«Æ×
%D 2004
%I
%X L-Lysine was produced by a microbial process utilizing a Corynebacterium glutamicum (ATCC 21799) strain. L-Lysine was purified from the cultivated medium by fixed-bed and simulated moving bed (SMB) chromatography. The separation conditions including pH, eluent concentration and Lys+ and Lys2+ adsorption isotherms were studied in batch adsorption. The column capacity, eluent flow rate and eluent concentration have been studied in fixed-bed chromatography. Maximum purification rate of lysine was obtained as 0.066 g/(g x h) (per gram resin and per hour) at an eluent flow rate of 10 mL/min in fixed-bed chromatography. The results obtained from SMB were 0.11 g/(g x h) for L-lysine purification rate and 96% for L-lysine recovery.
%K ion exchange chromatography
%K simulated moving bed
%K purification
%K L-lysine
L-Àµ°±Ëá
%K Àë×Ó½»»»É«Æ×
%K ·ÂÒÆ¶¯´²
%K ¹Ì¶¨´²
%K ¾»»¯
%K °ô×´¸Ë¾ú
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=1D095755A528FBEE&yid=D0E58B75BFD8E51C&vid=BC12EA701C895178&iid=E158A972A605785F&sid=6D6BFCF0101BC091&eid=E57FE519484CFB70&journal_id=1000-8713&journal_name=É«Æ×&referenced_num=0&reference_num=11