%0 Journal Article
%T Analysis and Stability Study on Nimotop Injections by RP-HPLC
尼莫通注射液的含量测定及其稳定性的研究
%A HU Yong-shi
%A TANG Qiu-hua
%A DU Qing-yun
%A
胡永狮
%A 汤秋华
%A 杜青云
%J 色谱
%D 2000
%I
%X A method was developed by using reversed-phase high performance liquid chromatography (HPLC) to analyze nimotop injections. Methyltestosterone was used as an internal standard. The separation was performed on a YWG C18 column with mobile phase of V (methanol):V (water) = 65:35 and detected at 238 nm. The linear concentration range of this method was 5.98 mumol/L-299.0 mumol/L. This method was simple, rapid and has been used to study the stability of nimotop injections. The experimental results showed that the nimotop was stable at higher temperature (50 degrees C) but unstable under light. Nimotop injection should be kept away from light.
%K high performance liquid chromatography
%K nimotop injection
%K methyltestosterone
%K stability
尼莫通注射液
%K 测定
%K HPLC
%K 稳定性
%K 尼莫地平
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=9BA2AC08419A7FD819A7AAA0C6C7A02C&yid=9806D0D4EAA9BED3&vid=13553B2D12F347E8&iid=E158A972A605785F&sid=09D368C679EC819B&eid=389106FB36CA8332&journal_id=1000-8713&journal_name=色谱&referenced_num=0&reference_num=1