%0 Journal Article
%T Analysis of 2 Acrylamido 2 Methyl Propane Sulfonic Acid by Thin Layer Chromatography<br>薄层色谱法分析2-丙烯酰胺基-2-甲基丙烷磺酸
%A Ma Zhi
%A Wei Tianjun
%A Feng Guangying
%A Liu Jingui
%A Zhao Zhijie
%A <br>马志
%A 魏天俊
%A 冯光瑛
%A 刘锦贵
%A 赵志杰
%J 色谱
%D 1999
%I 
%X A method for the analysis of 2-acrylamido-2-methyl propane sulfonic acid(AMPS) by TLC is described. The plate was Silica GF254. We selected benzene/methanol as developing agent from several developing systems and fixed the best ratio: V(benzene):V(methanol) = 2:1. The experiment indicated that the Rf value of AMPS was 0.36 while that of AM(acrylamide), the main impurity in crude AMPS sample, was 0.64. The minimum detectable limit of AMPS was 5 micrograms and the developing time was about 25 minutes. Compared with ether/methanol and chloroform/methanol, benzene/methanol system has the advantages of more easily controlling its ratio, better repeatability and much rapid developing rate. This method may be helpful in the control of AMPS in quality.
%K thin layer chromatography
%K 2
%K acrylamido
%K 2
%K methyl propane sulfonic acid
%K developing agent<br>薄层色谱
%K 丙烯酰胺基
%K 甲基丙烷磺酸
%K AMPS
%K 测定
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=D7F5F79B7B81B862CCB4A472C40B2EAE&yid=B914830F5B1D1078&vid=BCA2697F357F2001&iid=94C357A881DFC066&sid=37F781FD8E744761&eid=4ECB3941871FD391&journal_id=1000-8713&journal_name=色谱&referenced_num=0&reference_num=4