%0 Journal Article
%T Chiral Ion Pair Chromatography
手性离子对色谱法
%A X Li
%A S Zeng
%A
李新
%A 曾苏
%J 色谱
%D 1998
%I
%X A chiral counter ion dissolved in the mobile phase can be used to separate enantiomers of acids and amines. The principles and related separation variables have been reviewed. A successful enantiomeric separation is highly dependent on the features of counter ion chosen for the experiments. The most important properties of a suitable chiral reagent can be summarized as follows:(1) acid base character of counter ion;(2) hydrophobicity of counter ions;(3) presence of suitable funtional groups;(4) enantiomeric purity of counter ion, etc. It is also discussed about the influences of various chromatographic conditions and the applications of chiral ion pair chromatography.
%K ion pair chromatography
%K HPLC
%K counter ion
%K chiral separation
手性
%K 离子对色谱
%K 拆分
%K HPLC
%K 对映体分离
%K 药物
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=F65B1163FA62F63D173752AC334D12DF&yid=8CAA3A429E3EA654&vid=7801E6FC5AE9020C&iid=0B39A22176CE99FB&sid=7F5DDA4924737DF5&eid=B62E0EEFE746E568&journal_id=1000-8713&journal_name=色谱&referenced_num=3&reference_num=4