%0 Journal Article %T A Novel Instrumentation Circuit for Electrochemical Measurements %A Li-Te Yin %A Hung-Yu Wang %A Yang-Chiuan Lin %A Wen-Chung Huang %J Sensors %D 2012 %I MDPI AG %R 10.3390/s120709687 %X In this paper, a novel signal processing circuit which can be used for the measurement of H+ ion and urea concentration is presented. A potentiometric method is used to detect the concentrations of H+ ions and urea by using H+ ion-selective electrodes and urea electrodes, respectively. The experimental data shows that this measuring structure has a linear pH response for the concentration range within pH 2 and 12, and the dynamic range for urea concentration measurement is in the range of 0.25 to 64 mg/dL. The designed instrumentation circuit possesses a calibration function and it can be applied to different sensing electrodes for electrochemical analysis. It possesses the advantageous properties of being multi-purpose, easy calibration and low cost. %K instrumentation %K biosensor %K electrochemical measurement %K multi-purpose %U http://www.mdpi.com/1424-8220/12/7/9687