%0 Journal Article
%T Determination of cyanuric acid in milk and milk powder by high performance liquid chromatography-tandem mass spectrometry<br>高效液相色谱-串联质谱法测定牛奶和奶粉中的三聚氰酸
%A GUI Qianwen
%A LIU Han
%A ZHAO Zengyun
%A DING Tao
%A XU Jinzhong
%A SHEN Weijian
%A SHEN Chongyu
%A WU Bin
%A ZHANG Rui
%A <br>桂茜雯
%A 柳菡
%A 赵增运
%A 丁涛
%A 徐锦忠
%A 沈伟健
%A 沈崇钰
%A 吴斌
%A 张睿
%J 色谱
%D 2010
%I 
%X A method for the determination of cyanuric acid (CYA) in milk and milk powder was developed using high performance liquid chromatography-electrospray ionization tandem mass spectrometry (HPLC-ESI MS/MS). The target analyte was extracted from samples by acetonitrile, and the proteins were precipitated at the same time. The supernatant was cleaned up and enriched with a strong anion exchange column, analysed by HPLC-MS/MS with an AX column, and quantified by internal standard method. Good linearity was obtained in the range of 50~2000 μg/L. The recoveries were all ranged from 97% to 121% at three levels, 200, 500 and 1000 μg/kg, and the relative standard deviations (RSDs) were all below 4.8%. Limit of quantification (LOQ) was 200 μg/kg. The method has high accuracy and precision, the operation is fast, easy and suitable for the determination of CYA in milk and milk powder.
%K high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)
%K cyanuric acid
%K milk
%K milk powder<br>高效液相色谱-串联质谱
%K 三聚氰酸
%K 牛奶
%K 奶粉
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=F90598BA68F816FD131BEEC4280589F8&yid=140ECF96957D60B2&vid=D3E34374A0D77D7F&iid=9CF7A0430CBB2DFD&sid=EE7D0B10C851F35D&eid=D5B44BB3CCE27369&journal_id=1000-8713&journal_name=色谱&referenced_num=0&reference_num=15