%0 Journal Article
%T Separation Model of Small Molecules with SEC Columns and Micellar Mobile Phase<br>用SEC柱和胶束流动相分离小分子的模型
%A PENG Shun-jin
%A ZOU Qi-chao
%A ZHANG Jin-zhi
%A FANG Guang-rong
%A CHEN Zheng-guo
%A <br>彭顺金
%A 邹其超
%A 张金枝
%A 方光荣
%A 陈正国
%J 色谱
%D 2000
%I 
%X Small alkanol molecules were successfully separated with SEC method in combination with a micellar mobile phase.The separation model has been given in this system.The separation is based on the differential migration of the micelle and the surrounding water and the differential distribution of the solute between the micelle and aqueous phase,therefore,the separation mechanism is very similar to that of micella electrokinetic chromatography(MEKC). The retention volume of solute is related to the micellar concentration by theoretical treatment,through which the solute distribution coefficient between micelle and aqueous phase could be obtained.Two different SEC columns were employed for separation of some alkanols and the theoretical model is supported by the experimental results. The distribution coefficients obtained were in good agreement for these two columns.
%K size exclusion chromatography
%K micellar mobile phase
%K separation model
%K distribution coefficient<br>体积排阻色谱法
%K 胶束流动相
%K 小分子分离
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=D106544497D1E244&yid=9806D0D4EAA9BED3&vid=13553B2D12F347E8&iid=0B39A22176CE99FB&sid=DBF54A8E2A721A6D&eid=6270DC1B5693DDAF&journal_id=1000-8713&journal_name=色谱&referenced_num=0&reference_num=1