%0 Journal Article
%T Separation and Determination of the Ingredients of Cold Medicines by Capillary Electrophoresis with Amperometric Detection<br>高效毛细管电泳-安培法同时检测感冒药中的扑尔敏、扑热息痛和维生素C
%A Yang Bingyi
%A Mo Jinyuan
%A Yang Xiaoyun
%A Wang Lishi
%A <br>杨冰仪
%A 莫金垣
%A 杨晓云
%A 王立世
%J 色谱
%D 1999
%I 
%X Determination and separation of three ingredients--chlorphenamine maleate, acetaminophen and vitamin C in cold medicines by capillary electrophoresis with amperometric detection were carried out. The effects of detection potential and organic modifier were extensively investigated. Separation efficiency could be improved by adding 1, 2-propanediol into buffer. On optimizing condition, chlorphenamine maleate, acetaminophen and vitamin C were separated satisfactorily and eluted within 12 min. The detection limits were 0.02, 0.08 and 0.01 mg/L respectively. The ingredients in several cold medicines were detected successfully. The recoveries of the samples were 94.2%-102.8%. The method is simple, rapid and highly reliable for routine analysis.
%K capillary electrophoresis
%K amperometric detection
%K cold medicine<br>感冒药
%K 扑尔敏
%K 扑热息痛
%K 维生素C
%K CE
%K 测定
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=D7F5F79B7B81B862532005F5CF9A3336&yid=B914830F5B1D1078&vid=BCA2697F357F2001&iid=94C357A881DFC066&sid=F18BA6286A889C1C&eid=A33A8FD1432A4C3E&journal_id=1000-8713&journal_name=色谱&referenced_num=7&reference_num=6