%0 Journal Article
%T Determination of dimethyl fumarate in leather and textiles by gas chromatography-tandem mass spectrometry with solid phase extraction<br>气相色谱-串联质谱法测定皮革和纺织品中的富马酸二甲酯
%A ZHAO Yang
%A QI Xiaoxia
%A <br>赵洋
%A 戚晓霞
%J 色谱
%D 2010
%I 
%X An effective method for the determination of dimethyl fumarate (DMF) in leather and textiles by gas chromatography-tandem mass spectrometry (GC-MS/MS) was developed. Samples of leather or textiles were extracted with ethyl acetate and concentrated, DMF was separated on a VF-5ms column and analyzed by GC-MS/MS after solid phase extraction (SPE) process. The result shows that this method is sensitive, accurate and reliable. The linear relationship was perfect and the interference with background signal was further eliminated after pretreatment, SPE and GC-MS/MS analytical conditions were optimized. The average recoveries of DMF in leather and textiles at three levels ranged from 84% to 93%, the relative standard deviations (n=6) were lower than 7.2%, the limits of detection in the range from 0.012 to 0.039 mg/kg (S/N=3), the correlation coefficient was 0.9990 over the range 0.05~100 mg/L. It has been applied to routine determination of DMF in leather and textiles with satisfactory results.
%K gas chromatography-tandem mass spectrometry (GC-MS/MS)
%K solid phase extraction (SPE)
%K dimethyl fumarate (DMF)
%K leather
%K textiles<br>气相色谱-串联质谱
%K 固相萃取
%K 富马酸二甲酯
%K 皮革
%K 纺织品
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=99AA4D703C3CBA2C2DDCC6F3CB1DFC87&yid=140ECF96957D60B2&vid=D3E34374A0D77D7F&iid=CA4FD0336C81A37A&sid=318E4CC20AED4940&eid=9FFCC7AF50CAEBF7&journal_id=1000-8713&journal_name=色谱&referenced_num=1&reference_num=11