%0 Journal Article
%T The Determination of Melatonin in Health Caring Medicine for Specific Purposes by High Performance Liquid Chromatography Mass Spectrometry<br>高效液相色谱-质谱法测定特定用途保健药品中的褪黑激素
%A Chen Wenrui
%A Chen Yonghong
%A Hu Guochang
%A <br>陈文锐
%A 陈永红
%A 胡国昌
%J 色谱
%D 1998
%I 
%X A rapid and precise method for the determination of melatonin in health-caring medicine for specific purposes, based on high performance liquid chromatography-mass spectrometry, has been developed. The compound was identified using DAD UV spectrum and mass spectrum. Hypersil ODS column, 100 mm x 2.1 mm i.d., and mobile phase of methanol-water (70:30, V/V) were used for the assays. The quantitation was performed with external standard, and detection at 275 nm. The calibration curve of melatonin was linear in the range of 5-50 mg/L and the detection limit was ca. 0.2 ng.
%K high performance liquid chromatography/mass spectrometry
%K melatonin
%K health
%K caring medicine<br>褪黑激素
%K 保健药品
%K HPLC
%K MS
%K 分析
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=F65B1163FA62F63D1468876F8AE05319&yid=8CAA3A429E3EA654&vid=7801E6FC5AE9020C&iid=94C357A881DFC066&sid=9B95A71E6639C039&eid=FB36B1C076A263FA&journal_id=1000-8713&journal_name=色谱&referenced_num=6&reference_num=1