%0 Journal Article
%T Simultaneous Determination of Four Fluoroquinolone Residues in Fish by Ion-Pair High Performance Liquid Chromatography<br>离子对高效液相色谱法同时测定鱼类中四种喹诺酮类药物的残留
%A GUO Genhe
%A PAN Wei
%A SU Desen
%A CHEN Hanzhen
%A <br>郭根和
%A 潘葳
%A 苏德森
%A 陈涵贞
%J 色谱
%D 2005
%I 
%X An ion-pair high performance liquid chromatographic method with a fluorescence detector was established to determine four fluoroquinolone residues in fish. The chromatographic conditions were as follows: Waters microBondapak C18 column (3.9 mm i.d. x 300 mm, 10 microm) was used at 40 degres C with 11 mmol/L tetrabutylammonium bromide solution (pH 3.0) acetonitrile (94: 6, v/v) as the mobile phase with a flow rate of 1.0 mL/min, at the excitation wavelength of 280 nm and emission wavelength of 460 nm. The detection limit for fish was 1 microg/kg. The linear range was from 6-100 microg/kg, and correlation coefficients were more than 0.9995. At the levels of 10, 50 and 100 microg/kg, the recoveries were 76%-100% with relative standard deviations of less than 7%. The method developed can meet the requirement for residue analysis.
%K ion-pair high performance liquid chromatography
%K ofloxacin
%K norfloxacin
%K ciprofloxacin
%K enrofloxacin
%K fish<br>离子对高效液相色谱法
%K 氧氟沙星
%K 诺氟沙星
%K 环丙沙星
%K 恩诺沙星
%K 鱼
%K 测定
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=64F0ACDFCC8B3052&yid=2DD7160C83D0ACED&vid=EA389574707BDED3&iid=E158A972A605785F&sid=238BD7580EFCC5AE&eid=1E9426A299DC9FFD&journal_id=1000-8713&journal_name=色谱&referenced_num=18&reference_num=10