%0 Journal Article
%T Simultaneous determination of 5-component contents in kuaian anticold solution by high performance liquid chromatography]<br>高效液相色谱法同时测定快安抗感冒液中5种组分的含量
%A Y Wang
%A <br>王勇
%J 色谱
%D 1999
%I 
%X A reversed-phase, isocratic high performance liquid chromatographic method has been successfully used to separate and determine the 5 components simultaneously in Kuaian anticold solution. In the anticold solution, paracetamol, caffeine, DL-methylephedrine HCl, chlorpheniramine maleate and guaiacol glyceryl ether were analyzed on a NOVA-PAK C18 column (150 mm x 3.9 mm i.d., 5 microns) at 35 degrees C with V(acetonitrile):V(0.03 mol/L ammonium dihydrogen phosphate):V(0.004 mol/L sodium heptyl sulfonate):V(triethylamine) = 12:44:43.5:0.5 with pH adjusted to 3.0 by orthophosphoric acid as the mobile phase. The detection was performed at 220 nm and the injection volume was 15 microL. For the 5 components mentioned above the calibration curves were linear in a certain range. The recoveries were (99.6 +/- 1.3)%, (98.4 +/- 1.7)%, (98.0 +/- 1.5)%, (98.5 +/- 1.8)%, (100.3 +/- 1.7)% (n = 5) respectively.
%K HPLC
%K 组分分析
%K 抗感冒药
%K 快安抗感冒液
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=D7F5F79B7B81B862BC93CCBEBAAEDF84&yid=B914830F5B1D1078&vid=BCA2697F357F2001&iid=38B194292C032A66&sid=DC330B09A33F1455&eid=B7BFA4B351E4C682&journal_id=1000-8713&journal_name=色谱&referenced_num=3&reference_num=2