%0 Journal Article
%T A New Method for Separation of 2,4,6-Trinitrotoluene(TNT) and Its Metabolites by High Performance Liquid Chromatography(HPLC)<br>一种新的分离三硝基甲苯及其代谢产物的高效液相色谱方法
%A Yao Ming
%A <br>姚明
%J 色谱
%D 1995
%I 
%X n HPLC method is described for separation of TNT and its main reduction metabolites. Two columns(LC-C(18) and LC-CN)are connected in series and operated isocratically at 1.0mL/min with water-methanol-tetrahydrofuran(60 35 5 ). The baseline separation of 4-amino-2,6-dinitrotoluene(4A) and 2-amino-4,6-dinitrotoluene(2A) ,which are main metabolites of TNT,is obtained(Rs=2.1). All the TNT and itsmetabolites,including TNT,2,6-diamino-4-nitrotoluene(2,6-DA),2,4-diamino-6-nitrotoluene(2,4-DA),4-hydroxylamino-2, 6-Ainitrotoluene(4HA), 4A and 2A , can be separated from each other with this method.
%K high performance liquid chromatography
%K trinitrotoluene(or TNT)
%K metabolites<br>三甲基甲苯
%K 高效液相色谱
%K 代谢产物
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=2BD31EED9264A15932C9A7B9F68437BC&yid=BBCD5003575B2B5F&vid=FC0714F8D2EB605D&iid=38B194292C032A66&sid=E089FDF3CDAE8561&eid=A1266CF37D675CF1&journal_id=1000-8713&journal_name=色谱&referenced_num=0&reference_num=2