%0 Journal Article
%T Determination of Avermictin in Avermictin Tablet by High Performance Liquid Chromatography<br>高效液相色谱法测定阿弗菌素含量
%A Shao Yun
%A Hu Fengzu
%A Shi Zhixian
%A <br>邵斌贝
%A 胡凤祖
%A 师治贤
%J 色谱
%D 1998
%I 
%X A method for the separation and determination of avermictin in avermictin tablet by reversed-phase high performance liquid chromatography (RP-HPLC) was developed. Operating conditions were as follows: TSK-GEL C18 column, 250 mm x 4.6 mm i.d., MeOH-H2O (75:25, V/V) mobile phase with a flow rate of 1.0 mL/min, and UV detection at 245 nm. The results showed that the active constituents avermictin B1a and B1b can by separated effectively. The relative standard deviations were 2.56% and 1.31%, respectively (n = 6). The method is accurate, rapid and simple, and provides a scientific basis for industrial production and quality control of avermictin tablet.
%K high performance liquid chromatography
%K avermictin<br>阿弗菌素
%K HPLC
%K 驱虫药
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=F65B1163FA62F63DDBAAC61E05AE6CA6&yid=8CAA3A429E3EA654&vid=7801E6FC5AE9020C&iid=CA4FD0336C81A37A&sid=117F81797AB182FC&eid=7E8E8B150580E4AB&journal_id=1000-8713&journal_name=色谱&referenced_num=1&reference_num=2