%0 Journal Article
%T Determination of Multicomponent Contents in Anticold Solution by High Performance Liquid Chromatography<br>高效液相色谱法测定复方感冒液多组分含量
%A S Deng
%A J Zheng
%A <br>邓思珊
%A 郑金春
%J 色谱
%D 1997
%I 
%X A high performance liquid chromatographic method has been successfully used to separate and determine the six drugs in an anticold solution. In the anticold solution, potassium guaiacol sulfonate, acetaminophen, D,L-methylephedrine, and caffeine were analyzed with a column of Zorbax ODS, by using the mobile phase of MeOH-0.05 mol/L KH2PO4-H3PO4 (250 : 750 : 0.5) and UV detector at 214 nm, dextromethorphan HBr and chlorpheniramine maleate were analyzed with the same column, by usingthe mobile phase of MeOH-H2O-HsPO4-SLS (80 : 20 : 0.5 : 0.2) and UV detector at 260 nm. This method is proved to be very effective to separate the six drugs mentioned above. For potassium guaiacol sulfonate, acetaminophen, D,L-methylephedrine, caffeine, dextromethorphan HBr and chlorpheniramine, the response values were linear between 1.0-10 microg, 5.0-50 microg, 0.25-2.5 microg, 0.5-5 microg, 0.25-2.5 microg, 0.05-0.5 microg respectively and the recoveries were 100.53% +/- 1.12%, 100.19% +/- 0.58%, 99.4% +/- 1.60%, 99.55% +/- 1.01%, 99.37% +/- 1.52%, 99.01% +/- 1.20% (n=5) respectively.
%K high performance liquid chromatography
%K compound anticold solution
%K components analysis<br>高效液相色谱法
%K 复方感冒液
%K 成分分析
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=A0C7CB2C65AD7C6D4A81E731AD7ACD56&yid=5370399DC954B911&vid=23CCDDCD68FFCC2F&iid=CA4FD0336C81A37A&sid=987EDA49D8A7A635&eid=8E6AB9C3EBAAE921&journal_id=1000-8713&journal_name=色谱&referenced_num=2&reference_num=2