%0 Journal Article
%T Determination of nifedipine content and its uniformity in tablets by high performance liquid chromatography]
高效液相色谱法测定硝苯地平片含量及其含量均匀度
%A Y Xing
%A J Wang
%A
邢玉仁
%A 王杰
%J 色谱
%D 1999
%I
%X An HPLC method with diazepam as internal standard was developed to determine nifedipine content and its uniformity in tablets. The analytical column was a C18 column, the mobile phase consisted of V (methanol):V(triethylamine, pH 5.20) = 68:32. The detection was carried out with UV detector (lambda = 237 nm). Under this condition, the linear range was wide(8-80 mg/L) and the recovery was high (99.86%). The proposed method is simple and accurate and the decomposed product can be separated as well. Therefore, the quality of nifedipine tablets can be effectively controlled.
%K NULL
HPLC
%K 测定
%K 硝苯地平片
%K 均匀度
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=D7F5F79B7B81B86237F029D043D5DE39&yid=B914830F5B1D1078&vid=BCA2697F357F2001&iid=38B194292C032A66&sid=51C74DF6A16DA45B&eid=F637763636425CAF&journal_id=1000-8713&journal_name=色谱&referenced_num=1&reference_num=2