%0 Journal Article
%T Discussion of the Validation of Thin Layer Chromatographic Procedure in Pharmaceutical Analysis<br>药物分析中薄层色谱的方法认证
%A Lin Leming
%A Zhang Jun
%A <br>林乐明
%A 张军
%J 色谱
%D 1997
%I 
%X TLC has become a convenient, fast, robust, and cost efficient technique in pharmaceutical analysis because of its coherent features. The important analytical performance parameters are summarized, such as accuracy, precision, reproducibility, specificity, detection limit, quantitation limit, linearity and range, etc. The validation methods and the acceptance criteria are discussed for sample preparation, sample stability in solution and on plate, sample exposure time, robustness and quality of stationary and mobile phases, application of sample to plate, spot dimension and shape, temperature, humidity and chamber saturation, detection, and quantitation, etc. It is recommended that the definition of the validation parameters and the validation procedures for quantitative TLC should be described whenever the results are reported.
%K thin
%K layer chromatography
%K pharmaceutical analysis
%K method validation<br>薄层色谱法
%K 药物分析
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=A0C7CB2C65AD7C6D738871E8C86AF86A&yid=5370399DC954B911&vid=23CCDDCD68FFCC2F&iid=E158A972A605785F&sid=85002451B65CE0D1&eid=C2F76551C0111538&journal_id=1000-8713&journal_name=色谱&referenced_num=2&reference_num=9