%0 Journal Article
%T Study on the Separation of a-Amino Acid Enantiomers by High Performance Liquid Chromatography(HPLC)with Urea Derivative as Chiral Stationary Phase<br>脲衍生物型手性固定相分离α－氨基酸对映体的研究
%A Lu Haitao
%A Yun Zihou
%A <br>吕海涛
%A 云自厚
%J 色谱
%D 1995
%I 
%X sing HPLC with urea derivative as chiral stationary phaxe the separations of racemic N-3,5-dinitroben-zoyl amino acid butyl esters by normaland reversed-phase liquid chromatography have been investigated. Theresults showed that the separalion by normal-phase chromatography was better than that by reversed-phasechromatography,and the opposite elution order was obtained. We thought that the chiral recognition mightmainlv be controlled bv the asvmmetric carbon atom of the R-1-(a-naphthyl) ethylamine component. Ano-ther asymmetric carbon atom,i.e. the one in the amino acid components might only contribute to improvethe enantioselectivity. The mobile phase also acted as an important role for the enantiomer separation.
%K high performance liquid chromatography
%K urea derivative as chiral stationary phase
%K enan-tiomer
%K a-amino acids
%K enantiomer separation<br>高效液相色谱，脲衍生物型手性固定相，α－氨基酸，对映体分离
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=6E709DC38FA1D09A4B578DD0906875B5B44D4D294832BB8E&cid=6579068328FE643F&jid=4D81E042D77AFEC6881D14759692069C&aid=42DA7D425B8411AFE75EEA8EF2F9E1C6&yid=BBCD5003575B2B5F&vid=FC0714F8D2EB605D&iid=CA4FD0336C81A37A&journal_id=1000-8713&journal_name=色谱&referenced_num=0&reference_num=0