%0 Journal Article
%T Autonomous forward inference via DNA computing
%A Fu Yan
%A Li Gen
%A Li Yin
%A Meng Dazh
%A <br>Fu Yan
%A Li Gen
%A Li Yin and Meng Dazh
%J 自然科学进展
%D 2007
%I 
%X Recent studies direct the researchers into building DNA computing machines with intelligence, which is measured by three main points: autonomous, programmable and able to learn and adapt. Logical inference plays an important role in programmable information processing or computing. Here we present a new method to perform autonomous molecular forward inference for expert system. A novel repetitive recognition site (RRS) technique is invented to design rule-molecules in knowledge base. The inference engine runs autonomously by digesting the rule-molecule, using a Class IIB restriction enzyme PpiI. Concentration model has been built to show the feasibility of the inference process under ideal chemical reaction conditions. Moreover, we extend to implement a triggering communication between molecular automata, as a further application of the RRS technique in our model.
%K RRS technique
%K forward inference
%K triggering communication
%K molecular automaton<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=96E6E851B5104576C2DD9FC1FBCB69EF&jid=504AF8C1E5476CA7C4EC9DF6FEAC14AC&aid=9B75FC8C2A20316B741B4858DA1D3F9F&yid=A732AF04DDA03BB3&vid=BCA2697F357F2001&iid=B31275AF3241DB2D&sid=00B9006659EBD8AC&eid=20D29EF591CB2C94&journal_id=1002-008X&journal_name=自然科学进展&referenced_num=0&reference_num=0