%0 Journal Article
%T A Surface Plasmon Resonance Sensor for the Detection of Deoxynivalenol Using a Molecularly Imprinted Polymer
%A Sung-Wook Choi
%A Hyun-Joo Chang
%A Nari Lee
%A Hyang Sook Chun
%J Sensors
%D 2011
%I MDPI AG
%R 10.3390/s110908654
%X The aim of the present work was to investigate the feasibility of applying the molecular imprinting polymer technique to the detection of the mycotoxin deoxynivalenol (DON) using a surface plasmon resonance (SPR) transducer. A molecularly imprinted polypyrrole (MIPPy) film was prepared via electropolymerization of pyrrole onto a bare Au chip in the presence of a template DON molecule. Atomic force microscope SPR analysis showed that the MIPPy film was deposited homogeneously on the Au surface, with a thickness of 5 nm. The MIPPy¨CSPR sensor exhibited a linear response for the detection of DON in the range of 0.1¨C100 ng/mL (R2 = 0.988). The selectivity efficiency of the MIPPy film for DON and its acetylated analogs 3-ADON and 15-ADON was 100, 19, and 44%, respectively. The limit of detection for DON with the MIPPy¨CSPR for a standard solution was estimated at >1 ng/mL. These results suggest that the combination of SPR sensing with a MIPPy film as a synthetic receptor can be used to detect DON.
%K deoxynivalenol
%K polypyrrole
%K molecular imprinting polymer
%K surface plasmon resonance
%K synthetic receptor
%U http://www.mdpi.com/1424-8220/11/9/8654