%0 Journal Article
%T NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens
%A Anthony L. Keyburn
%A Trudi L. Bannam
%A Robert J. Moore
%A Julian I. Rood
%J Toxins
%D 2010
%I MDPI AG
%R 10.3390/toxins2071913
%X The Clostridium perfringens necrotic enteritis B-like toxin (NetB) is a recently discovered member of the ¦Â-barrel pore-forming toxin family and is produced by a subset of avian C. perfringens type A strains. NetB is cytotoxic for avian cells and is associated with avian necrotic enteritis. This review examines the current state of knowledge of NetB: its role in pathogenesis, its distribution and expression in C. perfringens and its vaccine£¿potential.
%K NetB
%K necrotic enteritis
%K Clostridium perfringens
%K pore-forming toxin
%U http://www.mdpi.com/2072-6651/2/7/1913