%0 Journal Article
%T Antiarrhythmic peptide AAP10 prevents ventricular arrhythmia in rabbit LQT2 model<br>
%A Bodi Chen
%A Xiaoqing Quan
%A Cuntai Zhang
%A Jiagao Lu
%A Rong Bai
%A Nian Liu
%A Yanfei Ruan
%A Jun Ke
%A Jin M
%A Liandong Li
%A Lei Ruan
%A <br>
%J 老年心脏病学杂志(英文版)
%D 2008
%I Science Press
%X Background and Objective Increased transmural dispersion ofrepolarization (TDR) has been shown to contribute to initiation and maintenance of ventricular arrhythmia in long QT syndromes (LQTS).Intercellular uncoupling through gap junctions is an important mechanism for maintaining TDR in both intact and diseased heart.The present study was to test the hypothesis that improving gap junction communication reduces TDR and prevents ventricular arrhythmia in rabbit LQT2 model.Methods An arterially perfused rabbi...
%K gap junction
%K long QT syndrome
%K transmural dispersion of repolarization
%K antiarrhythmic peptide<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=AD36F34DDC3BA7B0&jid=4DC702B3A2386A4814E2FF9CFB799B27&aid=E1CE9C5FA9493FAEAC44E6980B7A325A&yid=67289AFF6305E306&vid=94C357A881DFC066&iid=38B194292C032A66&sid=F260CE035846B3B8&eid=BBF7D98F9BEDEC74&journal_id=1671-5411&journal_name=Journalofgeriatriccardiology:JGC&referenced_num=0&reference_num=0