%0 Journal Article
%T Prognostic indicator by urinary microglobulin after renal stenting
%A Weifeng SHEN
%A Jun NI
%A Ruiyan ZHANG
%A Jian HU
%A Qi ZHANG
%A Jingyuan XIE
%A <br>Weifeng SHEN
%A Jun NI
%A Ruiyan ZHANG
%A Jian HU
%A Qi ZHANG
%A Jingyuan XIE
%J 老年心脏病学杂志(英文版)
%D 2005
%I Science Press
%X Objective To evaluate the effect of revascularization of the renal artery on urinary microglobulin in patients with coronary artery disease and significant renal artery stenosis (RAS). Methods Forty-four patients with coronary artery disease and severe RAS (luminal narrowing >70%) underwent percutaneous transluminal renal artery angioplasty (PTRA) and stenting, as well as percutane-ous coronary intervention. The urine -microglobulin ( o^-MG) and P2-Cmicroglobulin (P,-MG) at baseline and at 3 months after the procedures were measured. Procedural success rate, procedural complications, serum creatinine concentration at baseline and at 3-months were also recorded. Results At 3-months after the renal revascularization therapy, there was no significant change of urine o^-MG compared with that of the baseline, however, the urine (3,-MG decreased significantly 3-months after the treatment (237+ 187^g/L vs 377±173 |J.g/L, P<0.01). Multivariate analysis revealed that persistent elevation of urine was an independent predictor of severe events (including re-admission and renal failure) after renal revascularization therapy in patients with severe RAS (OR=3.01, 95% Cl 1.01-8.95, P=0.036). Conclusions In patients with coronary artery disease and severe RAS, revascularization with PTRA and stenting may improve renal tubular function, but a continuous high level of urinary microglobulins after intervention is associated with more frequent re-hospitalization and renal failure.
%K renal artery stenosis
%K percutaneous renal artery angioplasty
%K urinary microglobulin<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=AD36F34DDC3BA7B0&jid=4DC702B3A2386A4814E2FF9CFB799B27&aid=7A1470EC6B43ABE0C6903F4F9B659834&yid=2DD7160C83D0ACED&vid=0B39A22176CE99FB&iid=38B194292C032A66&sid=B0EBA60720995721&eid=E22B6B8FE86DD8F9&journal_id=1671-5411&journal_name=Journalofgeriatriccardiology:JGC&referenced_num=0&reference_num=15