%0 Journal Article
%T Nocturnal myocardial ischemic events and sleep-disordered breathing in patients with coronary artery disease
%A Wenli ZHANG
%A Shiwen WANG
%A Caiyi LU
%A Peng LIU
%A Rui CHEN
%A Xian JI
%A Yusheng ZHAO
%A <br>Wenli ZHANG
%A Shiwen WANG
%A Caiyi LU
%A Peng LIU
%A Rui CHEN
%A Xian JI
%A Yusheng ZHAO
%J 老年心脏病学杂志(英文版)
%D 2004
%I Science Press
%X To investigate the occurrence of nocturnal myocardial ischemia and its relationship with sleep-disordered breathing (apneas and oxygen desaturations) in patients with angina pectoris undergoing coronary an-giography. Methods Eighty-two men and 14 women referred for consideration of coronary intervention were randomly selected. Observation by an overnight sleep monitor and Holier recording were performed to study sleep-disordered breathing (oxyhemoglobin desaturations ^4% and apnea-hypopneas) , heart rates, and ST-seg-ment depressions ( ^ Imm, ^ 1 min) . Results Nocturnal ST-segment depressions occurred in 37% of the patients. ST-segment depression within 2 min after an apnea-hypopnea or desaturation occurred in 17% of the patients . This temporal association was seen in 21 % of the patients with nocturnal ST-segment depressions, more frequently in men (P <0.05) and more frequently in those with severe disordered breathing (P <0.05) . Most of these ST-segment depressions were preceded by a series of breathing events: repeated apnea-hypopneas or de-saturations or both in 73% of the patients. Conclusions Episodes of nocturnal myocardial ischemia are com-mon in patients with angina pectoris. A temporal relationship between sleep-disordered breathing and myocardial ischemia was present in some of our patients, and occurs more frequently in men and in those with severely dis-ordered breathing.
%K angina pectoris
%K myocardial ischemia
%K coronary artery disease
%K sleep-disordered breathing<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=AD36F34DDC3BA7B0&jid=4DC702B3A2386A4814E2FF9CFB799B27&aid=3B0892E1D1C8CA491C8CBEAE2C74A0FF&yid=D0E58B75BFD8E51C&vid=CA4FD0336C81A37A&iid=0B39A22176CE99FB&sid=869807E2D7BED9EC&eid=BB0EA31DB1B01173&journal_id=1671-5411&journal_name=Journalofgeriatriccardiology:JGC&referenced_num=0&reference_num=17