%0 Journal Article
%T hs-CRP is a potential predictor of no-reflow in patients with AMI after emergency PCI<br>
%A Jibing Du
%A ST Chen
%A W Wang
%A CY Zhou
%A GP Li
%A TG Huang
%A HL Cong
%A <br>
%J 老年心脏病学杂志(英文版)
%D 2008
%I Science Press
%X Objective The paper aims to determine whether the inflammation, a powerful risk factor that has been demonstrated for the development of coronary artery disease, plays a role in no-reflow phenomenon in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). Methods We prospectively analyzed 656 patients with AMI after primary PCI. Based on post-PCI angiography data, patients were divided into two groups: the no-reflow group (TIMI=2, n =60) and the reflow group (TIMI=3, n =596). Results Our results showed that the inflammatory factors including leukocyte count (×109/L) (10.90±4.04 vs. 9.12±2.98 P =0.002), hs-CRP (5.04±0.71 vs. 4.70±0.75 P =0.001) and other factor platelet count (×109/L) (210.96±33.42 vs. 196.41±46.06 P =0.033) in no-reflow group are significantly higher than those in reflow group, major adverse cardiac events happened in the patients with no-reflow are higher than in reflow patients no matter in hospital or at the end of follow-up.We also found the left ventricular ejection fraction (LVEF) dramatically decreased (58.65±9.34 vs. 51.29±11.38, P<0.001) and left ventricular end-diastolic dimension (LVEDD) significantly increased (49.94±6.75 mm vs. 54.66±6.68mm, P<0.001) in no-reflow patients at the end of followup. Conclusions Our results suggest that inflammation factors function in no-reflow phenomenon, and no-reflow is a serious complication after primary PCI which predicts poor left ventricular systolic functional recovery and mortality in patients with AMI.
%K No-reflow
%K inflammation factors
%K acute myocardial infarction
%K percutaneous coronary intervention<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=AD36F34DDC3BA7B0&jid=4DC702B3A2386A4814E2FF9CFB799B27&aid=8080ABA346FF888C0C9B91A60B51FA37&yid=67289AFF6305E306&vid=94C357A881DFC066&iid=E158A972A605785F&sid=F9F74EC1AA08A7B9&eid=8B59EA573021D671&journal_id=1671-5411&journal_name=Journalofgeriatriccardiology:JGC&referenced_num=0&reference_num=23