%0 Journal Article
%T Effect of puerarin on myocardial perfusion and ventricular wall motion in patients with acute coronary syndrome<br>
%A Ling Niu
%A Dongye Li
%A Yong Xia
%A Defeng Pan
%A Xiaoping Wang
%A Yan Yan
%A Li Liang
%A Tongda Xu
%A <br>
%J 老年心脏病学杂志(英文版)
%D 2008
%I Science Press
%X Objective To investigate the effects of puerarin(Pur)on myocardial perfusion and ventricular wall motion in patients withacute coronary syndrome(ACS).Methods Thirty-seven patients with ACS were randomly divided into two groups:conventionaltreatment group(n=17,11 males,range of age:32-80 years,average age:60.9±4.9 years)and Purtreatment group(n=20,12 males,rangeof age:40-76 years.average age:62.7±3.5 years).Patients in the conventional treatment group received standard treatment according tothe current guidelines,while patients in the Pur treatment group received intravenous administration of Pur(500 mg/day)for 10 daysplus conventional treatment.Real-time myocardial contrast echocardiography (RT-MCE) was performed to evaluate the change inmyocardial perfusion index (MPI)and veiltricular wall motion index(VWMI)at admission and 10 days after treatment.Results At10 days after treatment,MPI was significantly higher(P＜0.01)and VWMI significantly lower(P＜0.01)in the Pur group comparingwith those in the conventional group.Conclusions Puerarin might improve myocardial microcirculation perfusion and ventricularwall motion in patients with ACS.
%K acute coronary syndrome
%K myocardial perfusion index
%K ventricular wall motion index
%K puerarin<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=AD36F34DDC3BA7B0&jid=4DC702B3A2386A4814E2FF9CFB799B27&aid=A21E548E10A36D2D87ED727FEDB3FF2F&yid=67289AFF6305E306&vid=94C357A881DFC066&iid=38B194292C032A66&sid=7CE3F1F20DE6B307&eid=4C100B7696CE9E24&journal_id=1671-5411&journal_name=Journalofgeriatriccardiology:JGC&referenced_num=0&reference_num=12