%0 Journal Article %T Optical Slot-Waveguide Based Biochemical Sensors %A Carlos Angulo Barrios %J Sensors %D 2009 %I MDPI AG %R 10.3390/s90604751 %X Slot-waveguides allow light to be guided and strongly confined inside a nanometer-scale region of low refractive index. Thus stronger light-analyte interaction can be obtained as compared to that achievable by a conventional waveguide, in which the propagating beam is confined to the high-refractive-index core of the waveguide. In addition, slot-waveguides can be fabricated by employing CMOS compatible materials and technology, enabling miniaturization, integration with electronic, photonic and fluidic components in a chip, and mass production. These advantages have made the use of slot-waveguides for highly sensitive biochemical optical integrated sensors an emerging field. In this paper, recent achievements in slot-waveguide based biochemical sensing will be reviewed. These include slot-waveguide ring resonator based refractometric label-free biosensors, label-based optical sensing, and nano-opto-mechanical sensors. %K integrated optics %K slot-waveguides %K optical sensors %K biosensors %U http://www.mdpi.com/1424-8220/9/6/4751