%0 Journal Article
%T Using laser confocal scanning microscope to study ischemia-hypoxia injury in rat brain slice
%A WANG Xiaoying
%A <br>
%J 科学通报(英文版)
%D 2000
%I 
%X The level of lipid peroxidation and cellular necrosis in rat living brain slices during brain ischemia-hypoxia injury have been observed using a laser confocal scanning microscope (LCSM) with double labeling of fluorescent probes D-399 (2, 7-dichlorofluorescin diacetate) and propidium iodide (PI). The hypoxia and/or reoxygenation injury in rat brain slices is markedly decreased by pretreatment with L-NG-nitro-arginine (L-NNA) and N-acetylcysteine (NAC), showing that the nitric oxide (NO) and other free radicals play an important role in brain ischemia-hypoxia injury.
%K laser confocal scanning microscope
%K brain ischemia-hypoxia injury
%K lipid peroxide
%K 2
%K 7-dichlorofluorescin diacetate<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=96E6E851B5104576C2DD9FC1FBCB69EF&jid=DD6615BC9D2CFCE0B6F945E8D5314523&aid=0252B4C48D5631E7&yid=9806D0D4EAA9BED3&vid=94E7F66E6C42FA23&iid=CA4FD0336C81A37A&sid=2A3781E88AB1776F&eid=987EDA49D8A7A635&journal_id=1001-6538&journal_name=科学通报(英文版)&referenced_num=0&reference_num=6