%0 Journal Article
%T Synthesis of L-cystine bridged bis(p-cyclodextrin) and its cooperative binding toward guest molecules<br>Synthesis of L-cystine bridgedbis（β-cyclodextrin） and its cooperative binding toward guest molecules
%A LI Li
%A LI Xiaoyun
%A LIU Yu
%A <br>
%J 科学通报(英文版)
%D 2004
%I 
%X A novel β-cyclodextrin derivative, L-cystine bridged bis(β-cyclodextrin) 1 has been synthesized and characterized by1H NMR,13C NMR, IR, Raman and combustion analyses. Spectrofluorometric titrations have been performed in aqueous phosphate buffer solution (pH=7.20) at 25 °C to give the complex stability constants (KS) and Gibbs free energy changes ( ΔG°) for the stoichiometric 1:1 inclusion complexation of 1 with four dyes. The binding abilities and molecular selectivities are discussed from the viewpoint of size/shape-fit and electrostatic interactions between hosts and guests. 2D ROESY investigation for the complexation between host and guest further confirms the cooperative binding of bridged cyclodextrin 1 with guest.
%K L-cystine
%K birdged bis(cyclodextrin)
%K dye
%K cooperative binding<br>L-胱氨酸
%K β环糊精
%K 宾分子
%K 磷酸盐
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=96E6E851B5104576C2DD9FC1FBCB69EF&jid=DD6615BC9D2CFCE0B6F945E8D5314523&aid=12F8B72255C2A0969A28FC098FC21641&yid=D0E58B75BFD8E51C&vid=2A3781E88AB1776F&iid=0B39A22176CE99FB&sid=EDA22B444205D04A&eid=7F5DDA4924737DF5&journal_id=1001-6538&journal_name=科学通报(英文版)&referenced_num=0&reference_num=14