%0 Journal Article
%T Probing molecular interaction between transferrin and anti-transferrin by atomic force microscope
%A ZHENG Zhiwen
%A YANG Peihui
%A ZENG Gucheng
%A CAI Jiye
%A <br>ZHENG
%A Zhiwen
%A YANG
%A Peihui
%A ZENG
%A Gucheng
%A CAI
%A Jiye
%J 科学通报(英文版)
%D 2006
%I 
%X The interaction between transferrin (Tf) and its antibody was investigated by atomic force microscope. Tf-antibody was immobilized on the Au-coated glass slide, and the specific combination between antibody and antigen was also character-ized by AFM. The results showed that holo-transferrin was jogged with anti-transferrin, and binded anti-tran- sferrin more tightly than apo-transferrin. The force- distance curves revealed that the affinity of anti-trans- ferrin and holo-transferrin was much stronger than that of apo-transferrin.
%K holo-transferrin
%K apo-transferrin
%K anti-transferrin
%K AFM<br>转铁球蛋白
%K 抗转铁球蛋白
%K 分子间相互作用
%K 原子力显微镜
%K 生物大分子
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=96E6E851B5104576C2DD9FC1FBCB69EF&jid=DD6615BC9D2CFCE0B6F945E8D5314523&aid=1B4125F5B87E2C9868B5A03409F12BD5&yid=37904DC365DD7266&vid=987EDA49D8A7A635&iid=E158A972A605785F&sid=EB58C3052341AAA3&eid=A53D7AA35F9929AF&journal_id=1001-6538&journal_name=科学通报(英文版)&referenced_num=0&reference_num=11