%0 Journal Article
%T Marinamide, a novel alkaloid and its methyl ester produced by the application of mixed fermentation technique to two mangrove endophytic fungi from the South China Sea
%A ZHU Feng
%A <br>ZHU
%A Feng
%A LIN
%A Yongcheng
%J 科学通报(英文版)
%D 2006
%I 
%X A novel 1-isoquinolone analog desig- nated as marinamide (A) and its methyl ester (B), were produced by the application of mixed fermenta- tion technique to two mangrove endophytic fungi (strains Nos. 1924 and 3893) from the South China Sea. Their structures were elucidated by compre- hensive spectra methods (mainly by 2D NMR) as 4- (2-pyrrolyl)-1-isoquinolone-3-carboxylic acid (A) and methyl 4-(2-pyrrolyl)-1-isoquinolone-3-carboxylate (B), respectively. Compounds A and B were not obtained when either strain was cultured individually under the same conditions. The results showed that the appli- cation of mixed fermentation technique maybe rep- resents a potentially important approach to discover novel metabolites.
%K endophytic fungus
%K mixed fermentation
%K metabolite
%K al- kaloid<br>内生真菌
%K 混合发酵
%K 代谢物
%K 生物碱
%K 甲酯
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=96E6E851B5104576C2DD9FC1FBCB69EF&jid=DD6615BC9D2CFCE0B6F945E8D5314523&aid=A2110FFBCFD8FF1A43AE01016AD1B62C&yid=37904DC365DD7266&vid=987EDA49D8A7A635&iid=59906B3B2830C2C5&sid=30D259683AC50F0D&eid=95A5B7E5A2BF95B5&journal_id=1001-6538&journal_name=科学通报(英文版)&referenced_num=0&reference_num=37