%0 Journal Article
%T Effects of metal ions on recombinant calcineurin A subunit
%A Lijun Yan
%A Chunguang Yi
%A Qun Wei
%A <br>
%J 科学通报(英文版)
%D 2000
%I 
%X Effects of metal ions on activities and solution conformations of calcineurin A subunit have been examined. The ability of several metal ions to activate calcineurin A has been tested with Ni2+> Mn2+> Mg2+/Ca2+. The corresponding CD spectra and intrinsic fluorescent emission spectra show that calcineurin A exists in different metal ion-dependent conformation states. Effects of the different concentritions of Ni2+ on activities and solution conformations of calcineurin A have been tested too. Results indicate that effects of these metal ions to activate calcineurin are due to their conformational changes.
%K calcineurin
%K metal ion
%K CD spectrum
%K intrinsic fluorescent emission spectrum<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=96E6E851B5104576C2DD9FC1FBCB69EF&jid=DD6615BC9D2CFCE0B6F945E8D5314523&aid=370EF5DF8D0BB7EA&yid=9806D0D4EAA9BED3&vid=94E7F66E6C42FA23&iid=94C357A881DFC066&sid=FB36B1C076A263FA&eid=522844664D9E629A&journal_id=1001-6538&journal_name=科学通报(英文版)&referenced_num=0&reference_num=10