%0 Journal Article
%T Reconstruction of the most recent common ancestor sequences of SARS-Cov S gene and detection of adaptive evolution in the spike protein
%A ZHANGYuan
%A ZHENGNan
%A HAOPei
%A ZHONGYang
%J 科学通报(英文版)
%D 2004
%I 
%X The genome organization and expression strategy of severe acute respiratory syndrome coronavirus (SARS-CoV) have been described extensively. As a structural glycoprotein on the virion surface, the spike protein is responsible for binding to host cellular receptors and for the fusion between the viral envelope and the cellular membrane. It also induces neutralizing antibodies in
%K SARS冠状病毒
%K 自适应进化
%K 基因表达
%K 糖蛋白
%K 分子免疫学
%K 波峰病毒
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=96E6E851B5104576C2DD9FC1FBCB69EF&jid=DD6615BC9D2CFCE0B6F945E8D5314523&aid=C43850DFD2355DCB665EE16E59394727&yid=D0E58B75BFD8E51C&vid=2A3781E88AB1776F&iid=59906B3B2830C2C5&sid=C02C1722E0B3854F&eid=AF8A4A632EC02431&journal_id=1001-6538&journal_name=科学通报(英文版)&referenced_num=0&reference_num=0