%0 Journal Article
%T D-galactose/D-glucose-binding Protein from Escherichia coli as Probe for a Non-consuming Glucose Implantable Fluorescence Biosensor
%A Viviana Scognamiglio
%A Vincenzo Aurilia
%A Nunzio Cennamo
%A Paola Ringhieri
%A Luisa Iozzino
%A Micaela Tartaglia
%A Maria Staiano
%A Giuseppe Ruggiero
%A Pierangelo Orlando
%A Tullio Labella
%A Luigi Zeni
%A Annalisa Vitale
%A Sabato DĄŻAuria
%J Sensors
%D 2007
%I MDPI AG
%R 10.3390/s7102484
%X D-Galactose/D-glucose-binding protein from E. coli (GGBP) is a monomer thatbinds glucose with high affinity. The protein structure of GGBP is organized in twoprincipal domains linked by a hinge region that form the sugar-binding site. In this workwe show that the mutant form of GGBP at the amino acid position 182 can be utilized as aprobe for the development of a non-consuming analyte fluorescence biosensor to monitorthe glucose level in diabetes health care.
%K Biosensor
%K Optical sensing
%K Glucose
%K Diabetes
%K Fluorescence
%K Proteins
%U http://www.mdpi.com/1424-8220/7/10/2484